TFF3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TFF3 in rat small intestine tissue lysate with TFF3 polyclonal antibody (Cat # PAB19439) at 2 ug/mL.
Immunohistochemistry
Immunohistochemical staining of human brain cells with TFF3 polyclonal antibody (Cat # PAB19439) at 2.5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TFF3.
Immunogen
A synthetic peptide corresponding to 16 amino acids near C-terminus of human TFF3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
TFF3 antibody is predicted to not cross-react with other TFF family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TFF3 in rat small intestine tissue lysate with TFF3 polyclonal antibody (Cat # PAB19439) at 2 ug/mL.Immunohistochemistry
Immunohistochemical staining of human brain cells with TFF3 polyclonal antibody (Cat # PAB19439) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TFF3
Entrez GeneID
7033Protein Accession#
NP_003217Gene Name
TFF3
Gene Alias
HITF, ITF, TFI, hP1.B
Gene Description
trefoil factor 3 (intestinal)
Omim ID
600633Gene Ontology
HyperlinkGene Summary
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq
Other Designations
intestinal trefoil factor|secretory protein|trefoil factor 3|trefoil factor 3, HITF, human intestinal trefoil factor
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Interactome
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Disease
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Publication Reference
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Differential regional and cellular distribution of TFF3 peptide in the human brain.
Bernstein HG, Dobrowolny H, Trubner K, Steiner J, Bogerts B, Hoffmann W.
Amino Acids 2015 May; 47(5):1053.
Application：IHC, Human, Brains.
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Nrf2 Is Involved in Maintaining Hepatocyte Identity during Liver Regeneration.
Zou Y, Lee J, Nambiar SM, Hu M, Rui W, Bao Q, Chan JY, Dai G.
PLoS One 2014 Sep; 9(9):e107423.
Application：IHC-P, Mouse, Liver.
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Differential regional and cellular distribution of TFF3 peptide in the human brain.
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