NLRP13 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NLRP13 in K-562 cell lysate with NLRP13 polyclonal antibody (Cat # PAB19310) at 1 ug/mL.
Immunocytochemistry
Immunocytochemical staining of K-562 cells with NLRP13 polyclonal antibody (Cat # PAB19310) at 2.5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP13.
Immunogen
A synthetic peptide corresponding to 19 amino acids near N-terminus of human NLRP13.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunocytochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NLRP13 in K-562 cell lysate with NLRP13 polyclonal antibody (Cat # PAB19310) at 1 ug/mL.Immunocytochemistry
Immunocytochemical staining of K-562 cells with NLRP13 polyclonal antibody (Cat # PAB19310) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NLRP13
Entrez GeneID
126204Protein Accession#
EAW72420Gene Name
NLRP13
Gene Alias
CLR19.7, NALP13, NOD14, PAN13
Gene Description
NLR family, pyrin domain containing 13
Omim ID
609660Gene Ontology
HyperlinkGene Summary
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
Other Designations
NACHT, LRR and PYD containing protein 13|NACHT, leucine rich repeat and PYD containing 13|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
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Disease
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