ALDH18A1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
ALDH18A1 polyclonal antibody (Cat # PAB19003, 1 ug/mL) staining of MCF-7 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ALDH18A1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of humanALDH18A1.
Sequence
C-SEHGSLKYLH
Host
Goat
Theoretical MW (kDa)
85
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_002851.2; NP_001017423.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
ALDH18A1 polyclonal antibody (Cat # PAB19003, 1 ug/mL) staining of MCF-7 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — ALDH18A1
Entrez GeneID
5832Protein Accession#
NP_002851.2;NP_001017423.1Gene Name
ALDH18A1
Gene Alias
GSAS, MGC117316, P5CS, PYCS
Gene Description
aldehyde dehydrogenase 18 family, member A1
Omim ID
138250Gene Ontology
HyperlinkGene Summary
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000020159|OTTHUMP00000020160|delta1-pyrroline-5-carboxlate synthetase|glutamate gamma-semialdehyde synthetase|pyrroline-5-carboxlate synthetase|pyrroline-5-carboxylate synthetase|pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde sy
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com