SOS1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of human fetal brain (Lane 1) and human fetal liver (Lane 2) lysate with SOS1 polyclonal antibody (Cat # PAB18901) at 1 : 1000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOS1.
Immunogen
A synthetic peptide corresponding to amino acids at N-terminus of human SOS1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:10000-1:20000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human fetal brain (Lane 1) and human fetal liver (Lane 2) lysate with SOS1 polyclonal antibody (Cat # PAB18901) at 1 : 1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SOS1
Entrez GeneID
6654Protein Accession#
NP_005624Gene Name
SOS1
Gene Alias
GF1, GGF1, GINGF, HGF, NS4
Gene Description
son of sevenless homolog 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq
Other Designations
OTTHUMP00000128306|gingival fibromatosis, hereditary, 1|guanine nucleotide exchange factor|son of sevenless homolog 1
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Interactome
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Pathway
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Disease
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