REL polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of REL.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human REL.
Sequence
NDLNASNACIYN
Host
Goat
Theoretical MW (kDa)
70
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
REL polyclonal antibody (Cat # PAB18583) (0.5 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — REL
Entrez GeneID
5966Protein Accession#
NP_002899.1Gene Name
REL
Gene Alias
C-Rel
Gene Description
v-rel reticuloendotheliosis viral oncogene homolog (avian)
Omim ID
164910Gene Ontology
HyperlinkGene Summary
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM
Other Designations
C-Rel proto-oncogene protein|oncogene REL, avian reticuloendotheliosis|v-rel avian reticuloendotheliosis viral oncogene homolog|v-rel reticuloendotheliosis viral oncogene homolog
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Interactome
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Disease
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