IDO2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of IDO2.
Immunogen
A synthetic peptide corresponding to human IDO2.
Sequence
C-RDKTLESILHPR
Host
Goat
Theoretical MW (kDa)
47.07
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
IDO2 polyclonal antibody (Cat # PAB17233) (0.5 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IDO2
Entrez GeneID
169355Protein Accession#
NP_919270.2Gene Name
IDO2
Gene Alias
INDOL1
Gene Description
indoleamine 2,3-dioxygenase 2
Gene Ontology
HyperlinkGene Summary
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM
Other Designations
indoleamine 2,3-dioxygenase-like 1 protein|indoleamine-pyrrole 2,3 dioxygenase-like 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.
Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, Prendergast GC.
Cancer Research 2007 Aug; 67(15):7082.
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Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.
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