PROP1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PROP1.
Immunogen
A synthetic peptide corresponding to human PROP1.
Sequence
AERRRQAEKPKKGR-C
Host
Goat
Theoretical MW (kDa)
25
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PROP1
Entrez GeneID
5626Protein Accession#
NP_006252Gene Name
PROP1
Gene Alias
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Gene Description
PROP paired-like homeobox 1
Omim ID
601538Gene Ontology
HyperlinkGene Summary
PROP1 has both DNA-binding and transcriptional activation ability. Its expression leads to ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes, and caudomedial thyrotropes. Inactivating mutations in PROP1 result in deficiencies of luteinizing hormone (LH; MIM 152780), follicle-stimulating hormone (FSH; MIM 136530), growth hormone (GH; MIM 139250), prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency (CPHD; MIM 262600).[supplied by OMIM
Other Designations
OTTHUMP00000161487|prophet of Pit1, paired-like homeodomain transcription factor
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Interactome
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Disease
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Publication Reference
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Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD).
Kelberman D, Turton JP, Woods KS, Mehta A, Al-Khawari M, Greening J, Swift PG, Otonkoski T, Rhodes SJ, Dattani MT.
Clinical Endocrinology 2009 Jan; 70(1):96.
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Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD).
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