NUDC polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NUDC.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human NUDC.
Sequence
C-PNLGNGADLPNYR
Host
Goat
Theoretical MW (kDa)
38.2
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
NUDC polyclonal antibody (Cat # PAB16636) (0.3 ug/mL) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NUDC
Entrez GeneID
10726Protein Accession#
NP_006591.1Gene Name
NUDC
Gene Alias
HNUDC, MNUDC, NPD011
Gene Description
nuclear distribution gene C homolog (A. nidulans)
Omim ID
610325Gene Ontology
HyperlinkGene Summary
NudC was first identified as a regulator of nuclear movement in the asexual reproductive cycle of the filamentous fungus Aspergillus nidulans. Human NUDC is a nuclear movement protein that associates with dynein (see DYNC1H1; MIM 600112) (Aumais et al., 2003 [PubMed 12679384]).[supplied by OMIM
Other Designations
OTTHUMP00000004405|nuclear distribution gene C homolog
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Interactome
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Publication Reference
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hNUDC promotes the cell proliferation and differentiation in a leukemic cell line via activation of the thrombopoietin receptor (Mpl).
Tang YS, Zhang YP, Xu P.
Leukemia 2008 May; 22(5):1018.
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hNUDC promotes the cell proliferation and differentiation in a leukemic cell line via activation of the thrombopoietin receptor (Mpl).
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