GCNT3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GCNT3.
Immunogen
A synthetic peptide corresponding to C-terminus of human GCNT3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:2000-1:5000)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — GCNT3
Entrez GeneID
9245Gene Name
GCNT3
Gene Alias
C2/4GnT, C2GnT-M, C2GnT2, GnT-M
Gene Description
glucosaminyl (N-acetyl) transferase 3, mucin type
Omim ID
606836Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins
Other Designations
OTTHUMP00000163601|beta1,6-N-acetylglucosaminyltransferase
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Interactome
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Pathway
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Publication Reference
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Mucin biosynthesis: identification of the cis-regulatory elements of human C2GnT-M gene.
Tan S, Cheng PW.
American Journal of Respiratory Cell and Molecular Biology 2007 Jun; 36(6):737.
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C2GnT-M is downregulated in colorectal cancer and its re-expression causes growth inhibition of colon cancer cells.
Huang MC, Chen HY, Huang HC, Huang J, Liang JT, Shen TL, Lin NY, Ho CC, Cho IM, Hsu SM.
Oncogene 2006 Jun; 25(23):3267.
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Regulation of sialyl-Lewis x epitope expression by TNF-alpha and EGF in an airway carcinoma cell line.
Ishibashi Y, Inouye Y, Okano T, Taniguchi A.
Glycoconjugate Journal 2005 Feb; 22(1-2):53.
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Mucin biosynthesis: identification of the cis-regulatory elements of human C2GnT-M gene.
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