TNKS polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
HEK293 overexpressing TANK1 (Lane 2) and TANK2 (Lane 4) and probed with TNKS polyclonal antibody (Cat # PAB15673) (mock transfection in first lane). Lane three is empty.
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Specification
Product Description
Goat polyclonal antibody raised aganist partial recombinant TNKS.
Immunogen
Recombinant protein corresponding to N-terminus 120 amino acids of human TNKS.
Sequence
RECOMBINANT
Host
Goat
Theoretical MW (kDa)
141
Reactivity
Human
Specificity
In transfected HEK293 transiently expressing TANK1 a band of approximately 142 KDa is observed. This band is not observed in the non-transfected HEK293.
No cross-reactivity expected to TANK2.Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
HEK293 overexpressing TANK1 (Lane 2) and TANK2 (Lane 4) and probed with TNKS polyclonal antibody (Cat # PAB15673) (mock transfection in first lane). Lane three is empty. -
Gene Info — TNKS
Entrez GeneID
8658Protein Accession#
NP_003738.2Gene Name
TNKS
Gene Alias
PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1
Gene Description
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Omim ID
603303Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000115550
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Interactome
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Disease
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Publication Reference
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Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T.
Cancer Cell 2005 Jan; 7(1):25.
Application：WB, Human, HT-1080, HTC75 cells.
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Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
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