SLC39A4 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of SLC39A4.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human SLC39A4.
Sequence
C-RQPKPPHEGSRAD
Host
Goat
Theoretical MW (kDa)
66.2, 68.4
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC39A4
Entrez GeneID
55630Protein Accession#
NP_060237.2Gene Name
SLC39A4
Gene Alias
AEZ, FLJ20327, MGC74741, ZIP4
Gene Description
solute carrier family 39 (zinc transporter), member 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
acrodermatitis enteropathica, zinc-deficiency type|zinc transporter ZIP4
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Interactome
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Disease
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Publication Reference
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Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression.
Li M, Zhang Y, Liu Z, Bharadwaj U, Wang H, Wang X, Zhang S, Liuzzi JP, Chang SM, Cousins RJ, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao Q.
PNAS 2007 Nov; 104(47):18636.
Application：WB, Human, MIA PaCa-2 cells.
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Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression.
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