PAWR polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PAWR.
Immunogen
A mixture of synthetic peptide corresponding to amino acids at N-terminus and C-terminus of human PAWR.
Sequence
MATGGYRTSSGLGGS, QENKTLLKVVGQLTR
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — PAWR
Entrez GeneID
5074Protein Accession#
Q961Z0Gene Name
PAWR
Gene Alias
PAR4, Par-4
Gene Description
PRKC, apoptosis, WT1, regulator
Omim ID
601936Gene Ontology
HyperlinkGene Summary
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq
Other Designations
WT1-interacting protein|prostate apoptosis response protein 4|prostate apoptosis response protein PAR-4|transcriptional repressor PAR4
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Interactome
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Disease
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Publication Reference
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Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1.
Richard DJ, Schumacher V, Royer-Pokora B, Roberts SG.
Genes & Development 2001 Feb; 15(3):328.
Application：WB-Ce, Human, HeLa, 293, HL-60 cells.
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Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1.
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