NUP107 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NUP107 in A-549 cell lysate with NUP107 polyclonal antibody (Cat # PAB13392) at (A) 1 and (B) 2 ug/mL .
Immunocytochemistry
Immunocytochemical staining of A-549 cells with 10 ug/mL NUP107 polyclonal antibody (Cat # PAB13392).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NUP107.
Immunogen
A synthetic peptide corresponding to internal region 20 amino acids of human NUP107.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of NUP107 in A-549 cell lysate with NUP107 polyclonal antibody (Cat # PAB13392) at (A) 1 and (B) 2 ug/mL .Immunocytochemistry
Immunocytochemical staining of A-549 cells with 10 ug/mL NUP107 polyclonal antibody (Cat # PAB13392). -
Gene Info — NUP107
Entrez GeneID
57122Protein Accession#
P57740Gene Name
NUP107
Gene Alias
NUP84
Gene Description
nucleoporin 107kDa
Omim ID
607617Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Identification of host proteins required for HIV infection through a functional genomic screen.
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.
Science 2008 Jan; 319(5865):921.
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The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.
Orjalo AV, Arnaoutov A, Shen Z, Boyarchuk Y, Zeitlin SG, Fontoura B, Briggs S, Dasso M, Forbes DJ.
Molecular Biology of the Cell 2006 Sep; 17(9):3806.
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Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex.
Boehmer T, Enninga J, Dales S, Blobel G, Zhong H.
PNAS 2003 Feb; 100(3):981.
Application：IF, WB-Tr, Human, HeLa cells.
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Identification of host proteins required for HIV infection through a functional genomic screen.
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