DNAL1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DNAL1.
Immunogen
A synthetic peptide corresponding to C-terminus 17 amino acids of human DNAL1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of DNAL1 in NIH/3T3 cell lysate with DNAL1 polyclonal antibody (Cat # PAB13055) at (A) 1 and (B) 2 ug/mL .Immunocytochemistry
Immunocytochemical staining of BALB/3T3 cells with 2.5 ug/mL DNAL1 polyclonal antibody (Cat # PAB13055). -
Gene Info — DNAL1
Entrez GeneID
83544Protein Accession#
NP_113615Gene Name
DNAL1
Gene Alias
C14orf168, MGC12435
Gene Description
dynein, axonemal, light chain 1
Omim ID
610062Gene Ontology
HyperlinkGene Summary
DNAL1 is a component of outer dynein arms, which contain the molecular motors for ATP-dependent cilia movement (Horvath et al., 2005 [PubMed 15845866]).[supplied by OMIM
Other Designations
1700010H15RiK|axonemal dynein light chain|axonemal dynein light chain 1
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Interactome
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Disease
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Publication Reference
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Identification of host proteins required for HIV infection through a functional genomic screen.
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.
Science 2008 Jan; 319(5865):921.
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Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.
Horvath J, Fliegauf M, Olbrich H, Kispert A, King SM, Mitchison H, Zariwala MA, Knowles MR, Sudbrak R, Fekete G, Neesen J, Reinhardt R, Omran H.
American Journal of Respiratory Cell and Molecular Biology 2005 Jul; 33(1):41.
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Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry.
Olbrich H, Häffner K, Kispert A, Völkel A, Volz A, Sasmaz G, Reinhardt R, Hennig S, Lehrach H, Konietzko N, Zariwala M, Noone PG, Knowles M, Mitchison HM, Meeks M, Chung EM, Hildebrandt F, Sudbrak R, Omran H.
Nature Genetics 2002 Feb; 30(2):143.
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Identification of host proteins required for HIV infection through a functional genomic screen.
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