BCL2L14 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of BCL2L14 in U-937 cell lysates with BCL2L14 polyclonal antibody (Cat # PAB12903) at (A) 2.5 and (B) 5 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of mouse testis tissue using BCL2L14 polyclonal antibody (Cat # PAB12903) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BCL2L14.
Immunogen
A synthetic peptide corresponding to C-terminus 15 amino acids of human BCL2L14.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Although antibody should react with both isoforms, only the Bcl-GS protein has been observed.
Form
Liquid
Recommend Usage
Western Blot (2.5-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of BCL2L14 in U-937 cell lysates with BCL2L14 polyclonal antibody (Cat # PAB12903) at (A) 2.5 and (B) 5 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of mouse testis tissue using BCL2L14 polyclonal antibody (Cat # PAB12903) at 2 ug/mL . -
Gene Info — BCL2L14
Entrez GeneID
79370Protein Accession#
NM_030766Gene Name
BCL2L14
Gene Alias
BCLG
Gene Description
BCL2-like 14 (apoptosis facilitator)
Omim ID
606126Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq
Other Designations
BCL2-like 14|apoptosis regulator BCL-G
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Interactome
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Disease
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Publication Reference
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The Bcl-2 protein family and its role in the development of neoplastic disease.
Heiser D, Labi V, Erlacher M, Villunger A.
Experimental Gerontology 2004 Aug; 39(8):1125.
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The Bcl-2 family: roles in cell survival and oncogenesis.
Cory S, Huang DC, Adams JM.
Oncogene 2003 Nov; 22(53):8590.
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Bcl-G, a novel pro-apoptotic member of the Bcl-2 family.
Guo B, Godzik A, Reed JC.
The Journal of Biological Chemistry 2001 Jan; 276(4):2780.
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The Bcl-2 protein family and its role in the development of neoplastic disease.
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