PDE5A polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of COS-1 cells transfected withPDE5A by using PDE5A polyclonal antibody (Cat # PAB12359) at 1:2000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against PDE5A.
Immunogen
C terminal region of human PDE5A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody selectively detects proteins corresponding to the PDE5A isoform.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Transfected lysate)
Western blot analysis of COS-1 cells transfected withPDE5A by using PDE5A polyclonal antibody (Cat # PAB12359) at 1:2000 dilution.Immunohistochemistry
Immunoprecipitation
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Gene Info — PDE5A
Entrez GeneID
8654Gene Name
PDE5A
Gene Alias
CGB-PDE, CN5A, PDE5, PDE5A1
Gene Description
phosphodiesterase 5A, cGMP-specific
Omim ID
603310Gene Ontology
HyperlinkGene Summary
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase|phosphodiesterase 5A
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Interactome
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Pathway
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Disease
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