Kdr polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Kdr in Kdr induced HUVEC lysate (50 ug) using Kdr polyclonal antibody (Cat # PAB12163) (4 ug/mL).
Western Blot (Transfected lysate)
Western blot analysis of Kdr in CSF-1 receptor/Kdr chimera transfected lysate (20 ug) using Kdr polyclonal antibody (Cat # PAB12163) (6 ug/mL).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Kdr.
Immunogen
A synthetic peptide corresponding to amino acids 1200-1300 of mouse Kdr.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to VEGR-2.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:250-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of Kdr in Kdr induced HUVEC lysate (50 ug) using Kdr polyclonal antibody (Cat # PAB12163) (4 ug/mL).Western Blot (Transfected lysate)
Western blot analysis of Kdr in CSF-1 receptor/Kdr chimera transfected lysate (20 ug) using Kdr polyclonal antibody (Cat # PAB12163) (6 ug/mL). -
Gene Info — Kdr
Entrez GeneID
16542Gene Name
Kdr
Gene Alias
6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2
Gene Description
kinase insert domain protein receptor
Gene Ontology
HyperlinkOther Designations
OTTMUSP00000023578|VEGF receptor-2|vascular endothelial growth factor receptor- 2|vascular endothelial growth factor receptor-2|vascular endothelial growth factor receptor-3
-
Publication Reference
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis.
Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, Shyr Y, Matrisian LM, Carbone DP, Lin PC.
Cancer Cell 2004 Oct; 6(4):409.
Application：IF, Mouse, Gr+CD11b+, Gr+CD11b+/VEGFR2+, Gr+CD11b+/VEGFR2-, MMP9 null Gr+CD11b+ cells.
-
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.
Takahashi T, Yamaguchi S, Chida K, Shibuya M.
The EMBO Journal 2001 Jun; 20(11):2768.
Application：IP-WB, WB-Tr, Bovine, Mouse, MSS31, BAE cells.
-
Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells.
Rahimi N, Dayanir V, Lashkari K.
The Journal of Biological Chemistry 2000 Jun; 275(22):16986.
Application：WB, Pig, Pig aortic endothelial (PAE) cells.
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com