Dio3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Dio3.
Immunogen
A synthetic peptide corresponding to amino acids 250-300 of rat Dio3.
Host
Rabbit
Reactivity
Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (30% glycerol, 0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Detection of Dio3 in rat placenta using Dio3 polyclonal antibody (Cat # PAB12112). -
Gene Info — Dio3
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Publication Reference
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Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium.
Huang SA, Dorfman DM, Genest DR, Salvatore D, Larsen PR.
The Journal of Clinical Endocrinology and Metabolism 2003 Mar; 88(3):1384.
Application:IHC-P, Human, Fetal epithelium, Uteroplacental unit.
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Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes.
Baqui M, Botero D, Gereben B, Curcio C, Harney JW, Salvatore D, Sorimachi K, Larsen PR, Bianco AC.
The Journal of Biological Chemistry 2003 Jan; 278(2):1206.
Application:IF, WB-Tr, Human, HEK 293, NCLP-6E cells.
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A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase.
Huang SA, Fish SA, Dorfman DM, Salvatore D, Kozakewich HP, Mandel SJ, Larsen PR.
The Journal of Clinical Endocrinology and Metabolism 2002 Oct; 87(10):4457.
Application:IHC-P, Human, Human hepatic vascular tumors.
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Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium.
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