SIRT7 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SIRT7 in human liver lysates with SIRT7 polyclonal antibody (Cat # PAB12032).
Immunoprecipitation
SIRT7 immunoprecipitated from human liver lysates with SIRT7 polyclonal antibody (Cat # PAB12034) and further Western blotted with (A) SIRT7 polyclonal antibody (Cat # PAB12033) (B) SIRT7 polyclonal antibody (Cat # PAB12032).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SIRT7.
Immunogen
A synthetic peptide corresponding to amino acids 100-200 of human SIRT7.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SIRT7 in human liver lysates with SIRT7 polyclonal antibody (Cat # PAB12032).Immunoprecipitation
SIRT7 immunoprecipitated from human liver lysates with SIRT7 polyclonal antibody (Cat # PAB12034) and further Western blotted with (A) SIRT7 polyclonal antibody (Cat # PAB12033) (B) SIRT7 polyclonal antibody (Cat # PAB12032). -
Gene Info — SIRT7
Entrez GeneID
51547Protein Accession#
Q9NRC8Gene Name
SIRT7
Gene Alias
MGC126840, MGC126842, SIR2L7
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
Omim ID
606212Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
silent mating type information regulation 2, S.cerevisiae, homolog 7|sir2-related protein type 7|sirtuin 7|sirtuin type 7
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Interactome
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Publication Reference
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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.
Frye RA.
Biochemical and Biophysical Research Communications 2000 Jul; 273(2):793.
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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.
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