TP53BP1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TP53BP1.
Immunogen
A synthetic peptide corresponding to human TP53BP1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody is specific to human 53BP1 protein.
Form
Liquid
Recommend Usage
Immunocytochemistry (1:100-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400)
Western Blot (1:1000-1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TP53BP1 in untreated U-2 OS cell lysate with TP53BP1 polyclonal antibody (Cat # PAB11994).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
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Gene Info — TP53BP1
Entrez GeneID
7158Gene Name
TP53BP1
Gene Alias
53BP1, FLJ41424, MGC138366, p202
Gene Description
tumor protein p53 binding protein 1
Omim ID
605230Gene Ontology
HyperlinkGene Summary
1|tumor protein p53-binding protein
Other Designations
tumor protein 53-binding protein, 1|tumor protein p53-binding protein, 1
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Interactome
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Disease
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Publication Reference
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Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ.
Hsiao SJ, Smith S.
Journal of Cellular Biology 2009 Feb; 184(4):515.
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Functional dissection of human and mouse POT1 proteins.
Palm W, Hockemeyer D, Kibe T, de Lange T.
Molecular and Cellular Biology 2009 Jan; 29(2):471.
Application:IF, Mouse, MEF cells.
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Regulation of phosphoglucose isomerase/autocrine motility factor activities by the poly(ADP-ribose) polymerase family-14.
Yanagawa T, Funasaka T, Tsutsumi S, Hu H, Watanabe H, Raz A.
Cancer Research 2007 Sep; 67(18):8682.
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Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ.
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