LPAR2 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis using LPAR2 polyclonal antibody (Cat # PAB10124) at 5 ug/mL on McA-RH7777 cells transfected with LPAR2 protein in the absense (lane 1) and presense (lane 2) of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LPAR2.
Immunogen
A synthetic peptide corresponding to N-terminus of human LPAR2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (5 to 10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using LPAR2 polyclonal antibody (Cat # PAB10124) at 5 ug/mL on McA-RH7777 cells transfected with LPAR2 protein in the absense (lane 1) and presense (lane 2) of blocking peptide. -
Gene Info — LPAR2
Entrez GeneID
9170Gene Name
LPAR2
Gene Alias
EDG-4, EDG4, FLJ93869, LPA2
Gene Description
lysophosphatidic acid receptor 2
Omim ID
605110Gene Ontology
HyperlinkGene Summary
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
Other Designations
G protein-coupled receptor|LPA receptor EDG4|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4|lysophosphatidic acid receptor EDG4
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Interactome
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Pathway
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Publication Reference
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LPA2 receptor mediates mitogenic signals in human colon cancer cells.
Yun CC, Sun H, Wang D, Rusovici R, Castleberry A, Hall RA, Shim H.
American Journal of Physiology. Cell Physiology 2005 Jul; 289(1):C2.
Application：WB-Ce, WB-Tr, Human, SW480, Caco-2 cells.
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Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.
Goetzl EJ, An S.
FASEB Journal 1998 Dec; 12(15):1589.
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Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate.
An S, Goetzl EJ, Lee H.
Journal of Cellular Biochemistry. Supplement 1998 Dec; 30:147.
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LPA2 receptor mediates mitogenic signals in human colon cancer cells.
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