NTSR2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant NTSR2.
Immunogen
Recombinant protein corresponding to amino acids 150-200 of human NTSR2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — NTSR2
Entrez GeneID
23620Protein Accession#
NP_036476.1Gene Name
NTSR2
Gene Alias
NTR2
Gene Description
neurotensin receptor 2
Omim ID
605538Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq
Other Designations
levocabastine-sensitive neurotensin receptor|neurotensin receptor, type 2
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Pathway
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Disease
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