SLAMF6 (Human) Recombinant Protein
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More Files
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Enzyme-linked Immunoabsorbent Assay
Immobilized Human SLAMF6, hFc Tag at 0.2 ug/mL (100 uL/well) on the plate. Dose response curve for Biotinylated Anti-SLAMF6 Antibody, hFc Tag with the EC50 of 16.1 ng/mL determined by ELISA.
SEC-HPLC
The purity of Human SLAMF6 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human SLAMF6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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Specification
Product Description
Human SLAMF6 (Q96DU3-1, Gln22-Met226) partial recombinant protein with hFc tag at C-Terminus expressed in HEK293 cells.
Sequence
Gln22-Met226
Host
Human
Theoretical MW (kDa)
49.8
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The EC50 was 16.1 ng/mL, messured by ELISA at 0.2 ug/mL.
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human SLAMF6 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human SLAMF6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human SLAMF6, hFc Tag at 0.2 ug/mL (100 uL/well) on the plate. Dose response curve for Biotinylated Anti-SLAMF6 Antibody, hFc Tag with the EC50 of 16.1 ng/mL determined by ELISA.Functional Study
SDS-PAGE
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Gene Info — SLAMF6
Entrez GeneID
114836Protein Accession#
Q96DU3-1Gene Name
SLAMF6
Gene Alias
KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000
Gene Description
SLAM family member 6
Omim ID
606446Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. [provided by RefSeq
Other Designations
NTBA receptor|OTTHUMP00000024348|activating NK receptor|natural killer-, T- and B-cell antigen
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Interactome
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