FCRL2 (Human) Recombinant Protein
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Specification
Product Description
Human FCRL2 (Q96LA5-1, Leu20-Val401) partial recombinant protein with His tag at C-Terminus expressed in HEK293 cells.
Sequence
Leu20-Val401
Host
Human
Theoretical MW (kDa)
42.7
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human FCRL2 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human FCRL2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at -80°C for 12 Month.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human FCRL2, His Tag at 0.5 ug/mL (100 uL/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 0.13 ug/mL determined by ELISA.Functional Study
SDS-PAGE
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Gene Info — FCRL2
Entrez GeneID
79368Protein Accession#
Q96LA5-1Gene Name
FCRL2
Gene Alias
FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C
Gene Description
Fc receptor-like 2
Omim ID
606509Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
Fc receptor-like protein 2|OTTHUMP00000020928|OTTHUMP00000020929|SH2 domain containing phosphatase anchor protein 1|SH2 domain-containing phosphatase anchor protein 1
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Interactome
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Disease
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