FLNA (Human) Recombinant Protein
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More Files
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SEC-HPLC
The purity of Biotinylated Human Siglec-10 (R119A) is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Biotinylated Human Siglec-10 (R119A) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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Specification
Product Description
Human FLNA (Q96LC7-1, Met17-Thr546) partial recombinant protein with His-Avi tag at C-Terminus expressed in HEK293 cells.
Sequence
Met17-Thr546
Host
Human
Theoretical MW (kDa)
62.64
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Biotinylated Human Siglec-10 (R119A) is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Biotinylated Human Siglec-10 (R119A) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at -80°C for 12 Month.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Functional Study
SDS-PAGE
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Gene Info — FLNA
Entrez GeneID
2316Protein Accession#
Q96LC7-1Gene Name
FLNA
Gene Alias
ABP-280, ABPX, DKFZp434P031, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2
Gene Description
filamin A, alpha (actin binding protein 280)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000024320|actin-binding protein 280|filamin 1|filamin A, alpha
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Interactome
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Pathway
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Disease
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