ADORA2A (Human) Recombinant Protein
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Specification
Product Description
Human ADORA2A (P29274, Met1-Ser412) partial recombinant protein expressed in HEK293 cells.
Sequence
Met1-Ser412
Host
Human
Theoretical MW (kDa)
45.5
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Quality Control Testing
SEC-HPLC
SEC-HPLC
The purity of Human A2AR VLP is greater than 95% as determined by SEC-HPLC.
Recommend Usage
Biological Activity
ELISA
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS pH 7.4
Storage Instruction
Store at -80°C for 12 Month.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human A2AR VLP at 10 ug/mL (100 uL/Well) on the plate. Dose response curve for Anti-A2AR Antibody, hFc Tag with the EC50 of 0.87 ug/mL determined by ELISA.Functional Study
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Gene Info — ADORA2A
Entrez GeneID
135Protein Accession#
P29274Gene Name
ADORA2A
Gene Alias
ADORA2, RDC8, hA2aR
Gene Description
adenosine A2a receptor
Omim ID
102776Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine. [provided by RefSeq
Other Designations
adenosine A2 receptor|adenosine receptor subtype A2a
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Interactome
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