CD1B (Human) Recombinant Protein
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Specification
Product Description
Human CD1B (P29016, 18 a.a. - 303 a.a.) partial recombinant protein with His tag at N-terminus expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGS
Host
Escherichia coli
Theoretical MW (kDa)
34.2
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 90.0% by SDS-PAGE
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In 20mM Tris-HCl pH 8.0 (1 mM DTT, 0.2 M NaCl and 20% glycerol)
Storage Instruction
Store at 2°C to 8°C for 2-4 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — CD1B
Entrez GeneID
910Protein Accession#
P29016Gene Name
CD1B
Gene Alias
CD1, CD1A, MGC125990, MGC125991, R1
Gene Description
CD1b molecule
Omim ID
188360Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq
Other Designations
CD1B antigen|CD1B antigen, b polypeptide|OTTHUMP00000018908|T-cell surface glycoprotein CD1b|cortical thymocyte antigen CD1B|differentiation antigen CD1-alpha-3
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Interactome
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