CCL15 (Human) Recombinant Protein
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Specification
Product Description
Human CCL15 (Q16663, 46 a.a. - 113 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
SFHFAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI
Host
Escherichia coli
Theoretical MW (kDa)
7.4
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97.0% by SDS-PAGE
Activity
The ED50 is 2 - 4 ng/mL was measured by the ability to chemoattract THP-1 human acute monocytic leukemia cells.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL15
Entrez GeneID
6359Protein Accession#
Q16663Gene Name
CCL15
Gene Alias
HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15
Gene Description
chemokine (C-C motif) ligand 15
Omim ID
601393Gene Ontology
HyperlinkGene Summary
This gene, CCL15, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene is chemotactic for T cells and monocytes and induces N-acetyl-beta-D-glucosaminidase release in monocytes. It induces changes in intracellular calcium concentration in monocytes and is thought to act through the CCR1 receptor. Read-through transcripts are expressed that include exons from the downstream cytokine gene CCL14, and are represented as GeneID: 348249. [provided by RefSeq
Other Designations
CC chemokine 3|MIP-1 delta|OTTHUMP00000163955|chemokine CC-2|leukotactin 1|macrophage inflammatory protein 5|small inducible cytokine subfamily A (Cys-Cys), member 15
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