CCL19 (Human) Recombinant Protein
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Specification
Product Description
Human CCL19 (Q99731, 22 a.a. - 98 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
GTNDAEDCCLSVTQKPIPGYIVRNFHYLLIKDGCRVPAVVFTTLRGRQLCAPPDQPWVERIIQRLQRTSAKMKRRSS
Host
Escherichia coli
Theoretical MW (kDa)
8.800000000000001
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 98.0% by SDS-PAGE
Activity
The Biological activity is 7 - 40 ng/mL, was calculated by the ability to chemoattract Human T cells, corresponding to a specific activity of 25000 - 143000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL19
Entrez GeneID
6363Protein Accession#
Q99731Gene Name
CCL19
Gene Alias
CKb11, ELC, MGC34433, MIP-3b, MIP3B, SCYA19
Gene Description
chemokine (C-C motif) ligand 19
Omim ID
602227Gene Ontology
HyperlinkGene Summary
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq
Other Designations
CC chemokine ligand 19|CK beta-11|EBI1-ligand chemokine|OTTHUMP00000000531|OTTHUMP00000021295|beta chemokine exodus-3|exodus-3|macrophage inflammatory protein 3-beta|small inducible cytokine A19|small inducible cytokine subfamily A (Cys-Cys), member 19
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