CCL3 (Human) Recombinant Protein
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Specification
Product Description
Human CCL3 (P10147, 23 a.a. - 92 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
ASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA
Host
Escherichia coli
Theoretical MW (kDa)
7.8
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 98.0% by SDS-PAGE
Activity
The Biological activity is 1 - 10 ng/mL, was calculated by the ability of chemo-attraction of Human monocytes, corresponding to a specific activity of 100000 - 1000000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL3
Entrez GeneID
6348Protein Accession#
P10147Gene Name
CCL3
Gene Alias
G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3
Gene Description
chemokine (C-C motif) ligand 3
Gene Ontology
HyperlinkGene Summary
Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988 [PubMed 3279154]). Sherry et al. (1988) [PubMed 3058856] demonstrated 2 protein components of MIP1, called by them alpha and beta.[supplied by OMIM
Other Designations
LD78 alpha beta|small inducible cytokine A3 (homologous to mouse Mip-1a)
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