CCL13 (Human) Recombinant Protein
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Specification
Product Description
Human CCL13 (Q99616, 24 a.a. - 98 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
QPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT
Host
Escherichia coli
Theoretical MW (kDa)
8.6
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 96.0% by SDS-PAGE
Activity
The specific activity as determined by the ability of MCP-4 to chemoattract human monocytes at 10 - 100 ng/mL, corresponding to a specific activity of 10000 - 100000 units/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL13
Entrez GeneID
6357Protein Accession#
Q99616Gene Name
CCL13
Gene Alias
CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1
Gene Description
chemokine (C-C motif) ligand 13
Omim ID
601391Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq
Other Designations
CK-beta-10|monocyte chemoattractant protein 4|monocyte chemotactic protein 4|new CC chemokine 1|small inducible cytokine A13|small inducible cytokine subfamily A (Cys-Cys), member 13
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