CCL14 (Human) Recombinant Protein
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Specification
Product Description
Human CCL14 (Q16627, 22 a.a. - 93 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
TESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCSKPGIVFITKRGHS_x005F_x005F_x005F_x000D__x005F_x000D__x000D_ VCTNPSDKWVQDYIKDMKEN
Host
Escherichia coli
Theoretical MW (kDa)
8.4
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97.0% by SDS-PAGE
Activity
The Biological activity is 5 - 20 ng/mL, was determined by the ability to chemoattract Human monocytes, corresponding to a specific activity of 50000 - 200000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL14
Entrez GeneID
6358Protein Accession#
Q16627Gene Name
CCL14
Gene Alias
CC-1, CC-3, CKb1, HCC-1, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14
Gene Description
chemokine (C-C motif) ligand 14
Omim ID
601392Gene Ontology
HyperlinkGene Summary
This gene, CCL14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene CCL15, and are represented as GeneID: 348249. [provided by RefSeq
Other Designations
OTTHUMP00000176860|chemokine CC-1|chemokine CC-3|small inducible cytokine subfamily A (Cys-Cys), member 14
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