VEGFD (Human) Recombinant Protein
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Specification
Product Description
Human VEGFD partial recombinant protein with His tag in C-terminus expressed in?HEK293 cells.
Host
Human
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by SDS-PAGE.
Activity
ED50 is 3-4 ng/mL, measured by the ability to stimulate the proliferation of HUVEC cells.
Storage Buffer
Protein was lyophilized after extensive dialysis against PBS. Reconstitute the lyophilized powder in ddH2O to 100 ug/mL.
Storage Instruction
Lyophilized protein at room temperature for 3 weeks, should be stored at -20°C. Protein aliquots at 4°C for 2-7 days and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
Functional Study
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Gene Info — FIGF
Entrez GeneID
2277Protein Accession#
O43915Gene Name
FIGF
Gene Alias
VEGF-D, VEGFD
Gene Description
c-fos induced growth factor (vascular endothelial growth factor D)
Omim ID
300091Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. [provided by RefSeq
Other Designations
OTTHUMP00000022960|vascular endothelial growth factor D
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