TNFRSF10D (Human) Recombinant Protein
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Specification
Product Description
Human TNFRSF10D partial recombinant protein with hIgG-His tag in C-terminus expressed in Baculovirus cells.
Sequence
ATIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYHVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
Host
Viruses
Theoretical MW (kDa)
73.8
Form
Liquid
Preparation Method
Baculovirus expression system
Purification
chromatographic
Purity
> 90% as determined by SDS-PAGE.
Activity
ED50 ≤ 10 ng/mL, measured in a neutralizing assay using Jurkat human T lymphocyte in the presence of 2 ng/mL TRAIL.
Storage Buffer
Solution (0.5mg/mL) containing 1X PBS, pH 7.4, 10% glycerol.
Storage Instruction
Store at 4°C for one weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
Functional Study
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Gene Info — TNFRSF10D
Entrez GeneID
8793Protein Accession#
Q9UBN6Gene Name
TNFRSF10D
Gene Alias
CD264, DCR2, TRAILR4, TRUNDD
Gene Description
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Omim ID
603614Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq
Other Designations
TNF receptor-related receptor for TRAIL|TRAIL receptor 4|TRAIL receptor with a truncated death domain|decoy receptor 2|decoy with truncated death domain|tumor necrosis factor receptor superfamily, member 10d
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Interactome
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Pathway
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Disease
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