TNFRSF6B (Human) Recombinant Protein
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Specification
Product Description
Human TNFRSF6B partial recombinant protein with His tag in N-terminus expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH.
Host
Escherichia coli
Theoretical MW (kDa)
32.1
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
chromatographic
Purity
> 85% as determined by SDS-PAGE.
Storage Buffer
Solution (1 mg/mL) containing 20 mM Tris-HCl, pH 8.0, 10% glycerol, 0.4 M Urea.
Storage Instruction
Store at 4°C for one weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — TNFRSF6B
Entrez GeneID
8771Protein Accession#
O95407Gene Name
TNFRSF6B
Gene Alias
DCR3, DJ583P15.1.1, M68, TR6
Gene Description
tumor necrosis factor receptor superfamily, member 6b, decoy
Omim ID
603361Gene Ontology
HyperlinkGene Summary
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000031583|decoy receptor 3|tumor necrosis factor receptor superfamily, member 6b
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