TNFRSF9 (Human) Recombinant Protein
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Specification
Product Description
Human TNFRSF9 partial recombinant protein with His tag in N-terminus expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMFERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHSPQ
Host
Escherichia coli
Theoretical MW (kDa)
20
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
chromatographic
Purity
> 95% as determined by (a) RP-HPLC.(b) SDS-PAGE.
Storage Buffer
Solution (0.5 mg/mL) containing 20 mM Tris-HCl, pH 8.0, 10% glycerol, 0.1 M NaCl, 1 mM DTT.
Storage Instruction
Store at 4°C for 2-4 weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — TNFRSF9
Entrez GeneID
3604Protein Accession#
Q07011Gene Name
TNFRSF9
Gene Alias
4-1BB, CD137, CDw137, ILA, MGC2172
Gene Description
tumor necrosis factor receptor superfamily, member 9
Omim ID
602250Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq
Other Designations
4-1BB ligand receptor|CD137 antigen|OTTHUMP00000001360|OTTHUMP00000044294|T cell antigen ILA|homolog of mouse 4-1BB|induced by lymphocyte activation (ILA)|interleukin-activated receptor, homolog of mouse Ly63|receptor protein 4-1BB
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