OSM (Human) Recombinant Protein
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Specification
Product Description
Human OSM (P13725) recombinant protein expressed in Escherichia coli.
Sequence
AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFKWGESPNRSRRHSPHQALRKGVRR.
Host
Escherichia coli
Theoretical MW (kDa)
23.9
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97% by HPLC and SDS PAGE
Activity
The ED50 as determined by the dose-dependant stimulation of Human TF-1 cells is < 2 ng/mL, corresponding to a Specific Activity of 500,000 IU/mg.
Storage Buffer
1x PBS pH-7.4.
Storage Instruction
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles. -
Applications
Functional Study
SDS-PAGE
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Gene Info — OSM
Entrez GeneID
5008Protein Accession#
P13725Gene Name
OSM
Gene Alias
MGC20461
Gene Description
oncostatin M
Omim ID
165095Gene Ontology
HyperlinkGene Summary
Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. [provided by RefSeq
Other Designations
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