NPPA (Human) Recombinant Protein
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Specification
Product Description
Human NPPA (P01160, 26 a.a. - 123 a.a.) partial-length recombinant protein with His tag at N-Terminus expressed in Escherichia coli.
Sequence
MKHHHHHHNPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLTAPR.
Host
Escherichia coli
Theoretical MW (kDa)
11.7
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS PAGE
Storage Buffer
Lyophilized from 20 mM Tris buffer, 50 mM NaCl and 5% w/v trehalosa, pH 7.5.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
SDS-PAGE
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Gene Info — NPPA
Entrez GeneID
4878Protein Accession#
P01160Gene Name
NPPA
Gene Alias
ANF, ANP, ATFB6, CDD-ANF, PND
Gene Description
natriuretic peptide precursor A
Omim ID
108780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq
Other Designations
OTTHUMP00000002504|OTTHUMP00000044485|atrial natriuretic peptide|natriuretic peptide precursor A variant 2|pronatriodilatin
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