NOV (Human) Recombinant Protein
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Specification
Product Description
Human NOV (P48745) recombinant protein expressed in Escherichia coli.
Sequence
MQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM.
Host
Escherichia coli
Theoretical MW (kDa)
36.2
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by HPLC and SDS PAGE
Activity
Determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1.0 ug/mL, corresponding to a specific activity of > 1000 IU/mg. range of 10.0 -50.0 ng/mL, corresponding to a specific activity of 20,000-100,000 units/mg.
Storage Buffer
Lyophilized from 20mM Tris-HCl, pH 8.6 and 150 mM NaCl.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
Functional Study
SDS-PAGE
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Gene Info — NOV
Entrez GeneID
4856Protein Accession#
P48745Gene Name
NOV
Gene Alias
CCN3, IGFBP9
Gene Description
nephroblastoma overexpressed gene
Omim ID
164958Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq
Other Designations
nephroblastoma overexpressed
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Interactome
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