IL1F7 (Human) Recombinant protein
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Specification
Product Description
Human IL1F7 (Q9NZH6, 27 a.a. - 192 a.a) partial recombinant protein expressed in Escherichia Coli.
Sequence
MKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEK GSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYR_x005F_x005F_x005F_x000D__x005F_x000D__x000D_ AQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAE_x005F_x005F_x005F_x000D__x005F_x000D__x000D_ MSPSEVSD.
Host
Escherichia coli
Theoretical MW (kDa)
18.6
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS-PAGE.
Activity
As measured by the binding ability in a functional ELISA, immobilized IL1F7 at 1 ug/mL (100 uL/well) can bind rhIL-18 R/Fc Chimera with a linear range of 0.015 - 1 ug/mL.
Storage Buffer
Lyophilized from 20mM PB, 150mM NaCl and 2mM DTT, pH 7.4.
Storage Instruction
Lyophilized although stable at room temperature for 3 weeks. should be stored desiccated below -20°C. Upon reconstitution should be stored at 4°C between 2-7 days and for future use below -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL1F7
Entrez GeneID
27178Protein Accession#
Q9NZH6Gene Name
IL1F7
Gene Alias
FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1H4, IL1RP1
Gene Description
interleukin 1 family, member 7 (zeta)
Omim ID
605510Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
IL-1F7b (IL-1H4, IL-1H, IL-1RP1)|IL-1X protein|IL1F7 (canonical product IL-1F7b)|interleukin 1 family member 7|interleukin 1 family, member 7|interleukin 1, zeta|interleukin-1 homolog 4|interleukin-1 superfamily z|interleukin-1-related protein
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Interactome
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Disease
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