IL28B (Human) Recombinant protein
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Specification
Product Description
Human IL28B (Q8IZI9, 22 a.a. - 196 a.a) partial recombinant protein with His tag at C-terminal expressed in Sf9 cells.
Sequence
VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHHH.
Host
insect
Theoretical MW (kDa)
20.4
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purity
> 85% by SDS-PAGE.
Storage Buffer
In PBS, pH 7.4, 20% glycerol, 1mM EDTA and 0.1mM PMSF
Storage Instruction
Store at 4°C for 2~4 week. For long term storage store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — IL28B
Entrez GeneID
282617Protein Accession#
Q8IZI9Gene Name
IL28B
Gene Alias
IFNL3, IL-28B, IL28C
Gene Description
interleukin 28B (interferon, lambda 3)
Omim ID
607402Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq
Other Designations
interferon, lambda 3|interferon, lambda 4|interleukin 28B|interleukin 28C
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Pathway
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Disease
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