IL19 (Human) Recombinant protein
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Specification
Product Description
Human IL19 (Q9UHD0, 25 a.a. - 177 a.a) partial recombinant protein with His tag at C-terminal expressed in HEK293 cells.
Sequence
DGSHMLRRCL ISTDMHHIEE SFQEIKRAIQ AKDTFPNVTI LSTLETLQII KPLDVCCVTK NLLAFYVDRV FKDHQEPNPK ILRKISSIAN SFLYMQKTLR QCQEQRQCHC RQEATNATRV IHDNYDQLEV HAAAIKSLGE LDVFLAWINK NHEVMFSAHH HHHH
Host
Human
Theoretical MW (kDa)
19.1
Form
Liquid
Preparation Method
HEK 293T cell expression system
Purity
> 95% by SDS-PAGE.
Storage Buffer
In PBS, pH 7.4 and 10% glycerol
Storage Instruction
Store at 4°C for 2~4 week. For long term storage store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — IL19
Entrez GeneID
29949Protein Accession#
Q9UHD0Gene Name
IL19
Gene Alias
IL-10C, MDA1, NG.1, ZMDA1
Gene Description
interleukin 19
Omim ID
605687Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq
Other Designations
melanoma differentiation associated protein-like protein
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Pathway
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Disease
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