GDF7 (Human) Recombinant Protein
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Specification
Product Description
Human GDF7 partial recombinant protein expressed in Escherichia coli.
Sequence
TALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR
Host
Escherichia coli
Theoretical MW (kDa)
28
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purification
chromatographic
Purity
> 95% as determined by SDS-PAGE.
Activity
ED50 < 1.25 ug/mL, measured by inducing alkaline phosphatase production by mouse ATDC5 cells.
Storage Buffer
Lyophilized from a solution containing HCl. Reconstitute the lyophilized powder in ddH2O to 100 ug/mL.
Storage Instruction
Lyophilized protein at room temperature for 3 weeks, should be stored at -20°C. Protein aliquots at 4°C for 2-7 days and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
Functional Study
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Gene Info — GDF7
Entrez GeneID
151449Protein Accession#
Q7Z4P5Gene Name
GDF7
Gene Alias
BMP12
Gene Description
growth differentiation factor 7
Omim ID
604651Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq
Other Designations
OTTHUMP00000115986
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Pathway
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Disease
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