LGALS8 (Human) Recombinant Protein
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Specification
Product Description
Human LGALS8 full-length recombinant protein with His tag in N-terminus expressed in Escherichia coli.
Sequence
ThesequenceofthefirstfiveN-terminalaminoacidswasdeterminedandwasfoundtobeMet-Met-Leu-Ser-Leu
Host
Escherichia coli
Theoretical MW (kDa)
37.9
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
chromatographic
Purity
> 90% as determined by SDS-PAGE.
Activity
ED50 is 5-10 ug/mL, determined by the ability to agglutinate human red blood cells, corresponding to a specific activity of 100-200 IU/mg.
Storage Buffer
Solution (0.5 mg/mL) containing 20 mM Tris-HCl, pH 8.0, 10% glycerol, 0.1 M NaCl, 1 mM DTT.
Storage Instruction
Store at 4°C for 2-4 weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
Functional Study
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Gene Info — LGALS8
Entrez GeneID
3964Protein Accession#
O00214Gene Name
LGALS8
Gene Alias
Gal-8, PCTA-1, PCTA1, Po66-CBP
Gene Description
lectin, galactoside-binding, soluble, 8
Omim ID
606099Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000037854|Po66 carbohydrate binding protein|galectin 8|galectin-8|galectin-8g|prostate carcinoma tumor antigen 1
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