FGF23 (Human) Recombinant Protein
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Specification
Product Description
Human FGF23 recombinant protein with His tag in N-terminus expressed in Escherichia coli.
Sequence
MKHHHHHHASAEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTGPEGCRPFAKFI
Host
Escherichia coli
Theoretical MW (kDa)
8.67
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 90% as determined by SDS-PAGE.
Storage Buffer
Protein (0.5 mg/mL) was lyophilized from a solution containing 20 mM Tris, pH 7.5, 50 mM NaCl. Reconstitute the lyophilized powder in ddH2O to 0.5 mg/mL, and is not sterile! Please filter the product by an sterile filter before use.
Storage Instruction
Lyophilized protein should be stored at -20°C. Protein aliquots at 4°C for 2 weeks.
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — FGF23
Entrez GeneID
8074Protein Accession#
Q9GZV9Gene Name
FGF23
Gene Alias
ADHR, HPDR2, HYPF, PHPTC
Gene Description
fibroblast growth factor 23
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia. [provided by RefSeq
Other Designations
tumor-derived hypophosphatemia inducing factor
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