FGF18 (Human) Recombinant Protein
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Specification
Product Description
Human FGF18 partial recombinant protein with His tag in N-terminus expressed in Escherichia coli.
Sequence
MKHHHHHHASEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQKPFKYTTVTKRSRRIRPTHPA
Host
Escherichia coli
Theoretical MW (kDa)
22.3
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% as determined by densitometric image analysis.
Storage Buffer
Lyophilized from a solution containing 1X PBS, pH 7.4, 5% w/v trehalos. Reconstitute the lyophilized powder in ddH2O to 0.5 mg/mL, and is not sterile! Please filter the product by an sterile filter before use.
Storage Instruction
Lyophilized protein should be stored at -20°C. Protein aliquots at 4°C for 2 weeks.
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — FGF18
Entrez GeneID
8817Protein Accession#
O76093Gene Name
FGF18
Gene Alias
FGF-18, ZFGF5
Gene Description
fibroblast growth factor 18
Omim ID
603726Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq
Other Designations
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