EREG (Human) Recombinant Protein
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Specification
Product Description
Human EREG (O14944, 63 a.a.- 108 a.a.) partial-length recombinant protein with hIgG-His-Tag at C-terminal expressed in HEK293 cells.
Sequence
DGSMVSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
Host
Human
Theoretical MW (kDa)
32.6
Form
Liquid
Preparation Method
HEK 293T cell expression system
Purity
> 90% by SDS-PAGE
Activity
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 range ≤ 1ug/mL.
Storage Buffer
EREG protein (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
Functional Study
SDS-PAGE
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Gene Info — EREG
Entrez GeneID
2069Protein Accession#
O14944Gene Name
EREG
Gene Alias
ER
Gene Description
epiregulin
Omim ID
602061Gene Ontology
HyperlinkGene Summary
Epiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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