CTF1 (Human) Recombinant Protein
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Specification
Product Description
Human CTF1 (Q16619) recombinant protein expressed in Escherichia coli.
Sequence
MSRREGSLEDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGLSAPAPSHAGLPVHERLRLDAAALAALPPLLDAVCRRQAELNPRAPRLLRRLEDAARQARALGAAVEALLAALGAANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDLGQLLPGGSA.
Host
Escherichia coli
Theoretical MW (kDa)
21.2
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by HPLC and SDS PAGE
Activity
The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/mL, corresponding to a specific activity of < 1.0 106 IU/mg.
Storage Buffer
CTF-1 protein was lyophilized from a 0.2um filtered concentrated solution in 30% Acetonitrile and 0.1% TFA.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
Functional Study
SDS-PAGE
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Gene Info — CTF1
Entrez GeneID
1489Protein Accession#
Q16619Gene Name
CTF1
Gene Alias
CT-1, CT1
Gene Description
cardiotrophin 1
Omim ID
600435Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
cardiophin 1
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Interactome
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Pathway
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Disease
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