CLCF1 (Human) Recombinant Protein
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Specification
Product Description
Human CLCF1 (Q9UBD9) recombinant protein expressed in Escherichia coli.
Host
Escherichia coli
Theoretical MW (kDa)
22.7
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 98% by HPLC and SDS PAGE
Activity
The ED50 as determined by the dose-dependant stimulation of TF-1 cells is > 2 ng/mL, corresponding to a Specific Activity of 500,000 IU/mg.
Storage Buffer
Lyophilized from a concentrated (1mg/mL) solution in water containing 5mM sodium Phosphate buffer pH=7.5 and 5mM sodium chloride.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
Functional Study
SDS-PAGE
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Gene Info — CLCF1
Entrez GeneID
23529Protein Accession#
Q9UBD9Gene Name
CLCF1
Gene Alias
BSF3, CISS2, CLC, NNT1, NR6
Gene Description
cardiotrophin-like cytokine factor 1
Gene Ontology
HyperlinkGene Summary
CLCF1 belongs to the interleukin-6 (IL6; MIM 147620) family of cytokines, which are involved in cell signaling through phosphorylation of gp130 (IL6ST; MIM 600694). IL6 family members share similarity in gene structure and have a 4-helix bundle in their protein structure.[supplied by OMIM
Other Designations
B-cell stimulating factor 3|CRLF1 associated cytokine-like factor 1|cold-induced sweating syndrome 2|neurotrophin-1/B-cell stimulating factor-3
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