DEFB1 (Human) Recombinant Protein
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Specification
Product Description
Human DEFB1 (P60022) recombinant protein expressed in Escherichia coli.
Sequence
GNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK.
Host
Escherichia coli
Theoretical MW (kDa)
5
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 98% by HPLC and SDS PAGE
Activity
Determined by the ability to chemoattract CD34+ dendritic cells using a concentration range of 100-1000ng/mL corresponding to a specific activity of 1,000-10,000 IU/mg.
Storage Buffer
Lyophilized from 20mM PBS pH 7.4 and 130mM sodium chloride.
Storage Instruction
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles. -
Applications
Functional Study
SDS-PAGE
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Gene Info — DEFB1
Entrez GeneID
1672Protein Accession#
P60022Gene Name
DEFB1
Gene Alias
BD1, DEFB-1, DEFB101, HBD1, MGC51822
Gene Description
defensin, beta 1
Omim ID
602056Gene Ontology
HyperlinkGene Summary
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq
Other Designations
beta-defensin-1
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Interactome
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Disease
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